LIS1 Antibody [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NB200-326H

Catalog #
Availability
Size / Price
Qty
NB200-326H
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Conjugate
Catalog #
Alexa Fluor 350
NB200-326AF350
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Alexa Fluor 405
NB200-326AF405
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Alexa Fluor 488
NB200-326AF488
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Alexa Fluor 532
NB200-326AF532
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Alexa Fluor 594
NB200-326AF594
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Alexa Fluor 647
NB200-326AF647
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Alexa Fluor 700
NB200-326AF700
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Alexa Fluor 750
NB200-326AF750
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Alexa Fluor Plus 405
NB200-326AFP405
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Alexa Fluor Plus 488
NB200-326AFP488
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Alexa Fluor Plus 555
NB200-326AFP555
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Alexa Fluor Plus 594
NB200-326AFP594
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Alexa Fluor Plus 647
NB200-326AFP647
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Alexa Fluor Plus 680
NB200-326AFP680
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Allophycocyanin
NB200-326APC
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Biotin
NB200-326B
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CoraFluor 1
NB200-326CL1
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DyLight 350
NB200-326UV
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DyLight 405
NB200-326V
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DyLight 488
NB200-326G
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DyLight 550
NB200-326R
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DyLight 594
NB200-326DL594
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DyLight 650
NB200-326C
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DyLight 680
NB200-326FR
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DyLight 755
NB200-326IR
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FITC
NB200-326F
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Janelia Fluor 525
NB200-326JF525
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Janelia Fluor 549
NB200-326JF549
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Janelia Fluor 646
NB200-326JF646
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Janelia Fluor 669
NB200-326JF669
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mFluor Violet 450 SE
NB200-326MFV450
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mFluor Violet 500 SE
NB200-326MFV500
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mFluor Violet 610 SE
NB200-326MFV610
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PE
NB200-326PE
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PerCP
NB200-326PCP
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Forumulation
Catalog #
BSA Free
NB200-326
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

HRP

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all LIS1 Antibodies »

Product Specifications

Immunogen

Rabbits were immunized with a synthetic peptide, which represented a portion of human Lissencephaly-1 protein encoded in part by exons 3 and 4 (LocusLink ID 5048). Antibody was affinity purified using the peptide immobilized on solid support.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.

For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.

Applications for LIS1 Antibody [HRP]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Recommended applications are based on validated applications from the unconjugated base product NB200-326. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: LIS1

Lissencephaly (LIS), literally meaning smooth brain, has multiple causes. Agyria, i.e., brain without convolutions or gyri, was considered a rare malformation until recent progress in neuroradiology. With this technical advantage, a number of lissencephaly syndromes have been distinguished. Classic lissencephaly (type I) is a brain malformation caused by abnormal neuronal migration at 9 to 13 weeks' gestation, resulting in a spectrum of agyria, mixed agyria / pachygyria, and pachygyria. It is characterized by an abnormally thick and poorly organized cortex with 4 primitive layers, diffuse neuronal heterotopia, enlarged and dysmorphic ventricles, and often hypoplasia of the corpus callosum. Lissencephaly is found in association with facial abnormalities in Miller-Dieker syndrome and without other major anomalies in X-linked lissencephaly and isolated lissencephaly sequence (ILS). Subcortical band heterotopia (SBH) are bilateral and symmetric ribbons of gray matter found in the central white matter between the cortex and the ventricular surface and comprise the less severe end of the lissencephaly spectrum of malformations.

Alternate Names

LIS-1, LIS1PAF-AH alpha, LIS2, lissencephaly 1 protein, Lissencephaly-1 protein, MDCR, MDS, Miller-Dieker syndrome chromosome region, PAF acetylhydrolase 45 kDa subunit, PAFAH, PAF-AH 45 kDa subunit, PAFAH alpha, PAFAHA, platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa), platelet-activating factor acetylhydrolase IB subunit alpha, platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD), platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa, platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa)

Gene Symbol

PAFAH1B1

Additional LIS1 Products

Product Documents for LIS1 Antibody [HRP]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for LIS1 Antibody [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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