The Laminins comprise a growing family of disulfide-linked heterotrimers consisting of three genetically distinct polypeptide chains, designated alpha, beta and gamma. A major component of the basal lamina, Laminins play a crucial role in providing a scaffolding upon which tissues are assembled and which serves as a physical barrier separating specialized tissues. During embryogenesis and early development, cells migrate along basement membranes, which are required for the polarization of cells. The beta-2 laminin chain plays a role in melanoma spread, promoting tumor migration along the abluminal surface of vessel, a phenomenon which has been termed extra-vascular migratory metastasis.

Long Name

Laminin, beta 2

Alternate Names

LAMB2, Laminin beta 2

Gene Symbol

LAMB2

Additional Laminin S Products

Product Documents for Laminin S/Laminin beta 2 Antibody (C4) [Janelia Fluor® 669]

Product Datasheets

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COA

SDS

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Product Specific Notices for Laminin S/Laminin beta 2 Antibody (C4) [Janelia Fluor® 669]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Laminin S/Laminin beta 2 Antibody (C4) [Janelia Fluor® 669]

Novus Biologicals, part of Bio-Techne | Catalog # FAB2066JF669

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

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Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Applications for Laminin S/Laminin beta 2 Antibody (C4) [Janelia Fluor® 669]

Immunocytochemistry

Immunoprecipitation

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Laminin S