Kappa Light Chain Antibody (KLC2886R)

Unconjugated

Recombinant Monoclonal Rabbit IgG Kappa Clone # KLC2886R expressed in HEK293

Please see the vial label for concentration. If unlisted please contact technical services.

Recombinant full-length human Ig kappa chain (Uniprot: P01601)

Cell membrane, Secreted

This antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin' lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Monoclonal

Rabbit

IgG Kappa

22.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Protein A or G purified

10 mM PBS with 0.05% BSA

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C.