Irisin/FNDC5 Antibody (1056111) [Janelia Fluor® 549]
Novus Biologicals, part of Bio-Techne | Catalog # FAB94201I
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunocytochemistry
Label
Janelia Fluor 549
Antibody Source
Monoclonal Mouse IgG2A Clone # 1056111
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Synthetic peptide covering the C-term of the Irisin peptide sequences of the FNDC5 gene.
Glu97-Glu143
Accession # Q8NAU1
Glu97-Glu143
Accession # Q8NAU1
Specificity
Detects Irisin peptide in direct ELISA.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for Irisin/FNDC5 Antibody (1056111) [Janelia Fluor® 549]
Application
Recommended Usage
Immunocytochemistry
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Irisin/FNDC5
Irisin, also known as FNDC5, is a peptide hormone that is upregulated in skeletal muscle and subcutaneous adipose tissue during exercise. It induces expression of the mitochondrial proteins PPAR-gamma coactivator 1 alpha (PGC1a) and uncoupling protein-1 (UCP1). It contributes to the regulation of diabetes and obesity by inducing the transition of white adipose tissue into more metabolically active beige adipose tissue. Irisin also regulates neuronal cell differentiation, neurite outgrowth, and osteoblast differentiation.
Long Name
Fibronectin Type III Domain Containing 5
Alternate Names
FNDC5, FRCP2
Additional Irisin/FNDC5 Products
Product Documents for Irisin/FNDC5 Antibody (1056111) [Janelia Fluor® 549]
Product Specific Notices for Irisin/FNDC5 Antibody (1056111) [Janelia Fluor® 549]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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