Integrin alpha V beta 6 Antibody (7k) [Janelia Fluor® 525]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-50448JF525
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, CyTOF-ready
Label
Janelia Fluor 525
Antibody Source
Monoclonal Rat IgG2A Clone # 7k
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
3T3b6, mouse fibroblast expressing human Integrin alpha V beta 6
Specificity
Does not bind mouse.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Integrin alpha V beta 6 Antibody (7k) [Janelia Fluor® 525]
Application
Recommended Usage
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunoprecipitation
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Integrin alpha V beta 6
Integrin alpha V beta 6 (aVb6) is a heterodimeric adhesion protein that is exclusively expressed on subsets of epithelial cells, especially during development, after injury or inflammation, or on many carcinomas. Active aVb6 binds to the extracellular matrix proteins Fibronectin and Tenascin C as well as the TGF-beta latency-associated peptide (LAP). It cooperates with LTBP-1, Fibronectin, and PAR-1 to activate TGF-beta 1 or TGF-beta 3 from large latent complexes. aVb6 also plays a role in Treg development, tumor progression, and virus cellular entry.
Alternate Names
CD51, integrin subunit alpha V, ITGAV, MSK8, VNRA, VTNR
Gene Symbol
ITGAV
Additional Integrin alpha V beta 6 Products
Product Documents for Integrin alpha V beta 6 Antibody (7k) [Janelia Fluor® 525]
Product Specific Notices for Integrin alpha V beta 6 Antibody (7k) [Janelia Fluor® 525]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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