Influenza A H5N1 Hemagglutinin Antibody (1E6A7) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-75493

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Virus

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1E6A7

Format

BSA Free

Concentration

1 mg/ml

View all Influenza A H5N1 Hemagglutinin Antibodies »

Product Specifications

Immunogen

A peptide corresponding to 13 amino acids in the middle of the Hemagglutinin protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Influenza A H5N1 Hemagglutinin Antibody (1E6A7) - BSA Free

Western Blot: Influenza A H5N1 Hemagglutinin Antibody (1E6A7)BSA Free [NBP1-75493]

Western Blot: Influenza A H5N1 Hemagglutinin Antibody (1E6A7)BSA Free [NBP1-75493]

Western Blot: Influenza A Hemagglutinin Antibody (1E6A7) [NBP1-75493] - analysis of (A) 5 ng and (B) 25 ng of recombinant HA1 with Hemagglutinin antibody at 1 ug/mL

Applications for Influenza A H5N1 Hemagglutinin Antibody (1E6A7) - BSA Free

Application
Recommended Usage

ELISA

1 ug/ml

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Influenza A H5N1 Hemagglutinin

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found (2). These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong (3). The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low (4). HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability (5). While efforts were made to use relatively conserved regions of the viral sequence as the antigen, the influenza virus genome has drifted somewhat from what was first reported. However, this antibody was able to recognize peptides derrived from viruses from Indonesian human patients infected in 2007.

Additional Influenza A H5N1 Hemagglutinin Products

Product Documents for Influenza A H5N1 Hemagglutinin Antibody (1E6A7) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Influenza A H5N1 Hemagglutinin Antibody (1E6A7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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