Key Product Details

Species Reactivity

Canine

Applications

Western Blot, Immunocytochemistry

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 247002

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-6 Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant canine IL-6
Thr23-Met207
Accession # P41323

Specificity

Detects canine IL-6 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10%‑50% cross‑reactivity with recombinant eqine IL-6, recombinant human (rh) IL-6, recombinant mouse (rm) IL‑6, recombinant porcine IL-6, and recombinant rat (rr) IL-6 is observed and no cross-reactivity with rmCardiotrophin-1, rhCLC, rrCNTF, recombinant cotton rat IL-6, rmIL-11, rmLIF, or rmOncostatin M is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for IL-6 Antibody (247002) [Dylight 488]

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-6

IL-6 is a multifunctional cytokine that has an important role in host defense by regulating immune and inflammatory responses. It is expressed by a variety of normal and transformed cells including T cells, B cells, monocytes/macrophages, fibroblasts and various tumor cells. IL-6 has diverse biological functions, it stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Human IL-6 is active on murine cells but murine IL-6 is inactive on human cells.

Long Name

Interleukin 6

Alternate Names

BSF-2, BSF2, IFNB2, IL6, MGI-2A

Gene Symbol

IL6

Additional IL-6 Products

Product Documents for IL-6 Antibody (247002) [Dylight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-6 Antibody (247002) [Dylight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.