IL-4I1 Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-03586
Key Product Details
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Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
Scientific Data Images for IL-4I1 Antibody - BSA Free
Western Blot: IL-4I1 AntibodyAzide and BSA Free [NBP3-03586]
Western Blot: IL-4I1 Antibody [NBP3-03586] - Western blot analysis of extracts of various cell lines, using IL-4I1 antibody (NBP3-03586) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.Western Blot: IL-4I1 AntibodyAzide and BSA Free [NBP3-03586]
Western Blot: IL-4I1 Antibody [NBP3-03586] - Western blot analysis of extracts of THP-1 cells, using IL-4I1 antibody (NBP3-03586) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.Applications for IL-4I1 Antibody - BSA Free
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Background: IL-4I1
Interleukin 4 induced protein 1 (IL-4I1), also known as protein FIG-1 and L-amino acid oxidase, is encoded by a B-cell IL-4-inducible gene, FIG1, and is highly expressed in primary metastinal B-cell lymphomas. It belongs to the flavin monoamine oxidase family, FIG1 subfamily. Enzymological characterization reveals that IL-4I1 has L-amino acid oxidase activity with preference toward aromatic amino acids. Studies have shown that hIL-4I1 inhibited the proliferation of CD3-stimulated T lymphocytes with a similar effect on CD4(+) and CD8(+) T cells. Its inhibitory effect was dependent on enzymatic activity and H2O2 production. Its restricted expression to lymphoid tissues indicates that it may play an important function in the immune system.
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Additional IL-4I1 Products
Product Documents for IL-4I1 Antibody - BSA Free
Product Specific Notices for IL-4I1 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.