MCF-7 human breast cancer cell line (Korner, M and J.C. Reubi (2007) Peptides28:419) was stained with Human NPY1R Monoclonal Antibody (Catalog # MAB6400, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')₂Secondary Antibody (Catalog # F0101B).

Applications for Human NPY1R Antibody

Application

Recommended Usage

CyTOF-reported

This clone has been commercially reported for use in CyTOF®. Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

2.5 µg/10⁶ cells
Sample: MCF‑7 human breast cancer cell line

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Sterile PBS to a final concentration of 0.5 mg/mL. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: NPY1R

Neuropeptide Y receptor type 1 (NPY1R) is a 44 kDa (unglycosylated) member of the G protein coupled receptor 1 family. Human NPY1R is 384 amino acids (aa) in length and contains seven transmembrane regions and three potential sites for N-linked glycosylation. In addition, aa 338 is an S-palmitoyl cysteine lipid-binding site and aa 368 is a phosphoserine. Human NPY1R shares 94% and 93% aa sequence identity with mouse and rat NPY1R, respectively. Functionally, NPY1R is a receptor for neuropeptide Y and peptide YY.

Long Name

Neuropeptide Y Receptor Y1

Alternate Names

NPYY1

Entrez Gene IDs

4886 (Human); 18166 (Mouse)

Gene Symbol

NPY1R

UniProt

P25929

Additional NPY1R Products

Product Documents for Human NPY1R Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human NPY1R Antibody

For research use only

Citations
Reviews

Calculators
Flow Cytometry

Human NPY1R Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB6400

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all NPY1R Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human NPY1R Antibody

Detection of NPY1R in MCF‑7 Human Cell Line by Flow Cytometry.