Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

View all MUCDHL Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human MUCDHL
Gln26-Ala434
Accession # Q9HBB8

Specificity

Detects human MUCDHL in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant mouse MUCDHL is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Human MUCDHL Antibody

MUCDHL antibody in Human Kidney by Immunohistochemistry (IHC-P).

MUCDHL in Human Kidney.

MUCDHL was detected in immersion fixed paraffin-embedded sections of human kidney using 15 µg/mL Goat Anti-Human MUCDHL Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3826) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific labeling was localized to the plasma membrane of epithelial cells in collecting tubules. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Applications for Human MUCDHL Antibody

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human kidney

Western Blot

0.1 µg/mL
Sample: Recombinant Human MUCDHL

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MUCDHL

Mucin and cadherin-like protein (MUCDHL), also known as μ-protocadherin, is a 110 kDa type I transmembrane protein that is both O- and N-glycosylated. It is a calcium-dependant cell adhesion protein in the cadherin superfamily. MUCDHL is found on intestinal and renal epithelium. Human MUCDHL extracellular domain (ECD) contains four cadherin domains (residues 71-459) plus several mucin domains (residues 540-645). Alternate splicing creates four isoforms that differ in their mucin domains. In the region used as immunogen, human and mouse MUCDHL share 63% amino acid sequence identity.

Long Name

Mucin And Cadherin-like

Alternate Names

CDHR5, MU-PCDH, MUPCDH

Entrez Gene IDs

53841 (Human); 72040 (Mouse); 171554 (Rat)

Gene Symbol

CDHR5

UniProt

Q9HBB8

Additional MUCDHL Products

Product Documents for Human MUCDHL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human MUCDHL Antibody

For research use only

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