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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Alexa Fluor 700 (Excitation = 675-700 nm, Emission = 723 nm)

Antibody Source

Polyclonal Goat IgG

Product Specifications

Immunogen

E. coli-derived recombinant human CDC73
Met1-Glu260
Accession # Q6P1J9

Specificity

Detects human and mouse CDC73 in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human/Mouse CDC73 Alexa Fluor® 700-conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CDC73

CDC73 (also Parafibromin, HRPT2, and C1orf28) is a 60‑65 kDa member of the Cell Division Cycle family of proteins. It is found in adrenal, parathyroid and kidney, and serves as a regulator of Wnt signaling and a tumor suppressor by blocking c-myc expression. Human CDC73 is 531 amino acids (aa) in length. It contains multiple NLSs (aa 125‑139, 76‑92, and 393‑410) and a beta-catenin interaction sequence (aa 218‑263). There are at least two potential splice variants. One shows a five Lys substitution for aa 300‑531, while a second shows a 19 aa substitution for aa 298‑531. Full-length human and mouse CDC73 are completely (100%) identical in primary aa sequence.

Long Name

Cell Division Cycle 73

Alternate Names

HPT-JT, HRPT2, Parafibromin

Entrez Gene IDs

79577 (Human); 214498 (Mouse); 304832 (Rat)

Gene Symbol

CDC73

UniProt

Additional CDC73 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human/Mouse CDC73 Alexa Fluor® 700-conjugated Antibody


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

For research use only

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