Human Integrin alphaL/CD11a Fluorescein-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB3595F
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
FITC (Excitation = 488 nm, Emission = 515-545 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 345913
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Integrin alphaL/CD11a
Tyr26-Met1089 (Tyr660Ile)
Accession # CAA68747
Tyr26-Met1089 (Tyr660Ile)
Accession # CAA68747
Specificity
Detects human Integrin alphaL/CD11a in Western blots.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Human Integrin alphaL/CD11a Fluorescein-conjugated Antibody
Detection of Integrin alphaL/CD11a in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human Integrin aL/CD11a Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB3595F, filled histogram) or isotype control antibody (Catalog # IC002F, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human Integrin alphaL/CD11a Fluorescein-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood lymphocytes
Sample: Human peripheral blood lymphocytes
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Integrin alpha L/CD11a
Integrin subunit alphaL/CD11a is a 180 kDa type I TM glycoprotein that interacts only with Integrin beta2/CD18 to form LFA-1, a leukocyte adhesion protein which binds endothelial cell ICAM-1 through -4. Human Integrin alphaL contains a 1064 aa extracellular domain (ECD), a 20 aa TM sequence and a 58 aa cytoplasmic domain. The ECD contains seven repeats that form a beta-propeller structure and one inserted vWA domain (I domain) containing a metal ion-dependent adhesion site (MIDAS). Human and mouse Integrin alphaL ECD share 74% aa identity. CD11a has two splice variants, one which contains a 53 aa insert after Gln954, and a second which shows a deletion of aa 110-192.
Alternate Names
CD11a, ITGAL, LFA-1 alpha, Ly-15, Ly-21
Gene Symbol
ITGAL
UniProt
Additional Integrin alpha L/CD11a Products
Product Documents for Human Integrin alphaL/CD11a Fluorescein-conjugated Antibody
Product Specific Notices for Human Integrin alphaL/CD11a Fluorescein-conjugated Antibody
For research use only
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