Human DC-LAMP Lumenal Domain PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB4087P

R&D Systems, part of Bio-Techne
Discontinued Product
FAB4087P has been discontinued. View all DC-LAMP products.

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Polyclonal Goat IgG

View all DC-LAMP Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human DC‑LAMP Lumenal Domain
Asp21-Thr381
Accession # EAW78337

Specificity

Detects human DC‑LAMP Lumenal Domain in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human LAMP is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Human DC-LAMP Lumenal Domain PE-conjugated Antibody

Detection of DC-LAMP antibody in Human Mature Dendritic Cells antibody by Flow Cytometry.

Detection of DC‑LAMP in Human Mature Dendritic Cells by Flow Cytometry.

Human mature dendritic cells were stained with Goat Anti-Human DC-LAMP Lumenal Domain PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB4087P, filled histogram) or isotype control antibody (Catalog # IC108P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human DC-LAMP Lumenal Domain PE-conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human mature dendritic cells

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: DC-LAMP

DC-LAMP (Dendritic Cell Lysosome-associated Membrane Protein; also known as CD208 and LAMP3) is a 50‑70 kDa member of the LAMP family of proteins. Mature human DC-LAMP is a 389 amino acid (aa) type I transmembrane protein. It has a 254 aa lumenal N‑terminus and a short 14 aa cytoplasmic tail. The molecule is found in type II pneumocytes, interdigitating DC, and various tumors. DC-LAMP serves as a marker of human mature DC, and it may play a role in normal lysosome and endosome function. Over the region used as immunogen, human DC-LAMP shares 72% and 55% aa sequence identity with canine and mouse DC-LAMP, respectively.

Long Name

Dendritic Cell-lysosome-associated Membrane Glycoprotein

Alternate Names

CD208, DCLAMP, LAMP3, TSC403

Entrez Gene IDs

27074 (Human); 239739 (Mouse); 303801 (Rat)

Gene Symbol

LAMP3

UniProt

EAW78337

Additional DC-LAMP Products

Product Documents for Human DC-LAMP Lumenal Domain PE-conjugated Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human DC-LAMP Lumenal Domain PE-conjugated Antibody

For research use only

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