K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human CD98 APC-conjugated Monoclonal Antibody (Catalog # FAB5920A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human CD98 APC-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: K562 human chronic myelogenous leukemia cell line

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: CD98

CD98, also known as 4F2hc, is a ubiquitously expressed, 85-95 kDa member of the SLC3 (solute carrier 3) family of amino acid transporters. It is a type II transmembrane glycoprotein that covalently-associates with a variable number of small, 38-45 kDa, 12-transmembrane proteins that belong to the SLC7 family of molecules. The 120-130 kDa heterdimeric 4F2 complex is known to transport neutral or cationic amino acids with, or without, a contribution of sodium. It also interacts with Integrin beta1 and beta3 to promote cell polarization and migration. Notably, CD98 is "vertebrate-restricted," and its appearance evolutionarily has been linked to the onset of tumorigenesis. Over amino acids (aa) 105-529, human and mouse CD98 share 76% aa sequence identity.

Alternate Names

4F2, 4F2hc, CD98, CH98hc, FRP-1, SLC3A2

Entrez Gene IDs

6520 (Human); 17254 (Mouse)

Gene Symbol

SLC3A2

UniProt

P08195

Additional CD98 Products

Product Documents for Human CD98 APC-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human CD98 APC-conjugated Antibody

For research use only

Citations
Reviews

Human CD98 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB5920A

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all CD98 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human CD98 APC-conjugated Antibody

Detection of CD98 in K562 Human Cell Line by Flow Cytometry.

Applications for Human CD98 APC-conjugated Antibody

Flow Cytometry

Spectra Viewer

Plan Your Experiments

Formulation, Preparation, and Storage

Purification

Formulation

Shipping

Stability & Storage

Background: CD98

Alternate Names

Entrez Gene IDs

Gene Symbol

UniProt

Additional CD98 Products

Product Documents for Human CD98 APC-conjugated Antibody

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Human CD98 APC-conjugated Antibody

CONTACT INFORMATION

Stay Connected