HTRA2/Omi Antibody (23GB6110)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50458

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NBP3-50458-100ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Rabbit IgG Clone # 23GB6110

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all HTRA2/Omi Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human HTRA2/Omi (Uniprot: O43464)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HTRA2/Omi Antibody (23GB6110)

HTRA2/Omi Antibody (23GB6110)

Flow Cytometry: HTRA2/Omi Antibody (23GB6110)[NBP3-50458] -

Flow cytometric analysis of HTRA2/Omiexpression in HepG2 cells using HTRA2/Omi antibody (1:2,000). Green, isotype control; red, HTRA2.
HTRA2/Omi Antibody (23GB6110)

Western Blot: HTRA2/Omi Antibody (23GB6110)[NBP3-50458] -

Western blotting analysis using HTRA2/Omi antibody (1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (1:20,000) respectively. Image was developed using FeQ(TM) ECL Substrate Kit.

Applications for HTRA2/Omi Antibody (23GB6110)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: HTRA2/Omi

HtrA2 (Omi) is a serine protease that plays a significant role in programmed cell death, or apoptosis. Localized to the intermembrane space of the mitochondria, HtrA2 exists predominantly as two isoforms (1). In response to cellular stress signals, HtrA2 is released into the cytosol. One way that HtrA2 induces apoptosis is by binding to BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), and thereby inhibiting their caspase-inhibitory activity (2,3).

Long Name

High Temperature Requirement Protein-2

Alternate Names

Omi, PRSS25

Gene Symbol

HTRA2

Additional HTRA2/Omi Products

Product Documents for HTRA2/Omi Antibody (23GB6110)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for HTRA2/Omi Antibody (23GB6110)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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