HLA B7 Antibody (BB7.1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-48731

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-48731
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # BB7.1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all HLA B7 Antibodies »

Product Specifications

Immunogen

The immunogen used to generate this antibody corresponds to human HLA B.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse HLA B7 Antibody (BB7.1) (NBP3-48731) is a recombinant monoclonal antibody validated for use in Flow. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for HLA B7 Antibody (BB7.1)

HLA B7 Antibody (BB7.1)

Flow Cytometry: HLA B7 Antibody (BB7.1) [NBP3-48731] -

HLA B7 antibody [BB7.1] (NBP3-48731) detects HLA B7 protein by flow cytometry analysis. Sample: non-fixed and non-permeabilized PBMC; gated on granulocytes.
Black: Unlabelled sample was used as a control.
Red: HLA B7 antibody [BB7.1] (NBP3-48731) dilution: 1:50.
Acquisition of 20,000 events were collected using a Alexa Flour 488-conjugated secondary antibody for FACS analysis.
HLA B7 Antibody (BB7.1)

Flow Cytometry: HLA B7 Antibody (BB7.1) [NBP3-48731] -

HLA B7 antibody [BB7.1] (NBP3-48731) detects HLA B7 protein by flow cytometry analysis. Sample: non-fixed and non-permeabilized PBMC; gated on monocytes.
Black: Unlabelled sample was used as a control.
Red: HLA B7 antibody [BB7.1] (NBP3-48731) dilution: 1:50.
Acquisition of 20,000 events were collected using a Alexa Flour 488-conjugated secondary antibody for FACS analysis.

Applications for HLA B7 Antibody (BB7.1)

Application
Recommended Usage

Flow Cytometry

1:50-1:200

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HLA B7

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq]

Alternate Names

ankylosing spondylitis, AS, b'DT, Bw-22, Bw-4, Bw-41, Bw-44, Bw-45, Bw-46, Bw-47, Bw-48, Bw-50, Bw-52, Bw-53, Bw-54, Bw-55, Bw-56, Bw-57, Bw-58, Bw-60, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-12 alpha chain, HLA class I histocompatibility antigen, B-21 alpha chain, HLA class I histocompatibility antigen, B-5 alpha chain, HLA class I histocompatibility antigen, B-7 alpha chain, HLAB, HLA-B27, HLA-B73, leukocyte antigen class I-B, lymphocyte antigen, major histocompatibility complex, class I, B, MGC111087, MHC class I antigen B*13, MHC class I antigen B*14, MHC class I antigen B*15, MHC class I antigen B*18, MHC class I antigen B*27, MHC class I antigen B*35, MHC class I antigen B*37, MHC class I antigen B*38, MHC class I antigen B*39, MHC class I antigen B*40, MHC class I antigen B*41, MHC class I antigen B*42, MHC class I antigen B*44, MHC class I antigen B*45, MHC class I antigen B*46, MHC class I antigen B*47, MHC class I antigen B*48, MHC class I antigen B*49, MHC class I antigen B*50, MHC class I antigen B*51, MHC class I antigen B*52, MHC class I antigen B*53, MHC class I antigen B*54, MHC class I antigen B*55, MHC class I antigen B*56, MHC class I antigen B*57, MHC class I antigen B*58, MHC class I antigen B*59, MHC class I antigen B*67, MHC class I antigen B*7, MHC class I antigen B*73, MHC class I antigen B*78, MHC class I antigen B*8, MHC class I antigen B*81, MHC class I antigen B*82, MHC class I antigen GN00104, MHC class I antigen HLA-B heavy chain, MHC class I antigen SHCHA, MHC Class I HLA heavy chain, MHC HLA-B cell surface glycoprotein, SPDA1

Gene Symbol

HLA-B

Additional HLA B7 Products

Product Documents for HLA B7 Antibody (BB7.1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HLA B7 Antibody (BB7.1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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