HBcAg Antibody (H50) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-64452

Novus Biologicals, part of Bio-Techne
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NB100-64452
NB100-64452-0.025mg
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Key Product Details

Species Reactivity

Validated:

Virus

Cited:

Virus

Applications

Validated:

Immunohistochemistry

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # H50

Format

BSA Free

Concentration

0.5 mg/ml

View all HBcAg Antibodies »

Product Specifications

Immunogen

Native HBcAg

Specificity

Recognises the core antigen.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Description

Novus Biologicals Mouse HBcAg Antibody (H50) - BSA Free (NB100-64452) is a monoclonal antibody validated for use in IHC. Anti-HBcAg Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Applications for HBcAg Antibody (H50) - BSA Free

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Use in Immunohistochemistry reported in scientific literature (PMID: 30221736).

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

BSA Free

Preservative

<0.1% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HBcAg

Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.

Alternate Names

c, Core antigen, HBc, HBcAg, Hepatitis B Virus core antigen

Gene Symbol

C

Additional HBcAg Products

Product Documents for HBcAg Antibody (H50) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for HBcAg Antibody (H50) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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