GPR17 Antibody (CL10474) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44216JF646

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP3-44216AF350

Alexa Fluor 405

NBP3-44216AF405

Alexa Fluor 488

NBP3-44216AF488

Alexa Fluor 532

NBP3-44216AF532

Alexa Fluor 594

NBP3-44216AF594

Alexa Fluor 647

NBP3-44216AF647

Alexa Fluor 700

NBP3-44216AF700

Alexa Fluor 750

NBP3-44216AF750

Allophycocyanin

NBP3-44216APC

Biotin

NBP3-44216B

CoraFluor 1

NBP3-44216CL1

DyLight 350

NBP3-44216UV

DyLight 405

NBP3-44216V

DyLight 488

NBP3-44216G

DyLight 550

NBP3-44216R

DyLight 594

NBP3-44216DL594

DyLight 650

NBP3-44216C

DyLight 680

NBP3-44216FR

DyLight 755

NBP3-44216IR

FITC

NBP3-44216F

HRP

NBP3-44216H

Janelia Fluor 525

NBP3-44216JF525

Janelia Fluor 549

NBP3-44216JF549

Janelia Fluor 669

NBP3-44216JF669

mFluor Violet 450 SE

NBP3-44216MFV450

mFluor Violet 500 SE

NBP3-44216MFV500

mFluor Violet 610 SE

NBP3-44216MFV610

PE

NBP3-44216PE

PerCP

NBP3-44216PCP

Forumulation

Catalog #

BSA Free

NBP3-07993

Azide and BSA Free

NBP3-44216

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot

Label

Janelia Fluor 646

Antibody Source

Monoclonal Mouse IgG₁ Clone # CL10474

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all GPR17 Antibodies »

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of Q13304, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for GPR17 Antibody (CL10474) [Janelia Fluor® 646]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GPR17

GPR17, a former orphan G-coupled protein is specifically activated by P2Y and CysLT endogenous ligands, leading to both adenylyl cyclase inhibition and intracellular calcium increases. In both rats and humans GPR17 expressed in the organs which suffer ischemic damage, like the brain, heart and kidneys. Studies by Ciana, et. al. have shown that inhibition of GPR17 reduces ischemic damage in a rat focal ischemia model. These results suggest GPR17 is the common molecular target mediating brain damage by nucleotides and CysLTs.

Long Name

G Protein-coupled Receptor 17

Alternate Names

P2Y-like Receptor, R12, UDP/CysLT Receptor

Gene Symbol

GPR17

Additional GPR17 Products

Product Documents for GPR17 Antibody (CL10474) [Janelia Fluor® 646]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for GPR17 Antibody (CL10474) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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