GABA-A R gamma 2 Antibody
R&D Systems, part of Bio-Techne | Catalog # PPS072
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat, Bovine, Chicken, Primate, Zebrafish
Cited:
Human
Applications
Validated:
Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit Serum
Product Specifications
Immunogen
GABA-A R gamma 2
Specificity
Bovine, human, mouse, and rat ~44-47 kDa gamma2-subunit of the GABAA Receptor in Western blots.
Clonality
Polyclonal
Host
Rabbit
Isotype
Serum
Scientific Data Images for GABA-A R gamma 2 Antibody
Detection of GABAAR gamma2 by Western Blot.
Western blot of rat brain lysate showing specific immunolabeling of the approximately 44-47 kDa gamma 2 subunit of the GABAAR.Detection of GABA-A R gamma 2 by Western Blot
Comparative analysis of NLRP3 expression across treatment groups using Western blot. Values are expressed as mean ± SEM, n = 6. Data were analyzed by One-way ANOVA followed by Tukey’s multiple comparison test. (a) Western blot analysis of NLRP3 expression in treatment groups. (b) Densitometric analysis of NLRP3 levels normalized to GAPDH. (* p < 0.05 ALP vs. Disease control, ** p < 0.01 DSF vs. Disease control, *** p < 0.001 ALP + DSF vs. Disease control.) (c) Graphical representation of NLRP3 protein expression levels across experimental groups. **** p < 0.0001 Normal control vs. Disease control, ****ap < 0.0001 Disease control vs. ALP + DSF, *** p < 0.001 Disease control vs. DSF, * p < 0.05 Normal Control vs. ALP, *a p < 0.05 Disease Control vs. ALP, *b p < 0.05 Normal Control vs. DSF. (d) Protein ladder reference image (Gel and Blot view). Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/40430581), licensed under a CC-BY license. Not internally tested by R&D Systems.Applications for GABA-A R gamma 2 Antibody
Application
Recommended Usage
Western Blot
1:1000 dilution
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50 μL of unpurified rabbit serum.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
For long-term storage, ≤ -20° C is recommended. Product is stable at ≤ -20° C for at least 1 year.
Background: GABA-A R gamma 2
References
- Darlison, M.G. et al. (2005) Cell. Mol. Neurobiol. 25:607.
- Akabas, M.H. (2004) Int. Rev. Neurobiol. 62:1.
- Song, M. and R.O. Messing (2005) Cell. Mol. Life Sci. 62:119.
- Krishek, B.J. et al. (1994) Neuron 12:1081.
- Keller, C.A. et al. (2004) J. Neurosci. 24:5881.
- Moss, S.J. et al. (1992) J. Biol. Chem. 267:14470.
Long Name
gamma-Aminobutyric Acid Type A Receptor, gamma-2 Polypeptide
Alternate Names
GABAAR gamma 2, GABAARg2, GABRG2
Gene Symbol
GABRG2
Additional GABA-A R gamma 2 Products
Product Documents for GABA-A R gamma 2 Antibody
Product Specific Notices for GABA-A R gamma 2 Antibody
For research use only
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