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FXYD5/Dysadherin Antibody (CL14039) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24586

Novus Biologicals, part of Bio-Techne
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NBP3-24586-100ul
NBP3-24586-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL14039

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from Q96DB9, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Description

Novus Biologicals Mouse FXYD5/Dysadherin Antibody (CL14039) - BSA Free (NBP3-24586) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for FXYD5/Dysadherin Antibody (CL14039) - BSA Free

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14039) [NBP3-24586]

Staining of human tonsil shows moderate membranous positivity in lymphoid cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14039) [NBP3-24586]

Staining of human fallopian tube shows moderate membranous and cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: FXYD5/Dysadherin Antibody (CL14039) [NBP3-24586]

Staining of human breast cancer shows strong membranous positivity in tumor cells.

Applications for FXYD5/Dysadherin Antibody (CL14039) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FXYD5/Dysadherin

Dysadherin encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane.

Long Name

FXYD Domain-containing Ion Transport Regulator 5

Alternate Names

DYSAD, Dysadherin, EF-8, IWU1, KCT1, OIT2, PRO6241, RIC

Gene Symbol

FXYD5

Additional FXYD5/Dysadherin Products

Product Documents for FXYD5/Dysadherin Antibody (CL14039) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FXYD5/Dysadherin Antibody (CL14039) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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