ENPP-4 Antibody - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81466
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Immunohistochemistry-Paraffin: ENPP-4 Antibody [NBP1-81466]
Immunohistochemistry-Paraffin: ENPP4 Antibody [NBP1-81466] - Staining of human kidney shows cytoplasmic, membranous and nuclear positivity in renal tubules.Applications for ENPP-4 Antibody - BSA Free
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Background: ENPP-4
ENPP-4 (Ectonucleotide pyrophosphatase/phosphodiesterase 4; NPP4) belongs to a group of ecto-enzymes which regulate the availability of extracellular nucleotides. ENPP-4 hydrolyzes phosphodiester bonds in nucleotides with a preference for adenine nucleotides. It cleaves the diadenosine compounds Ap3A and Ap4a which are released from the dense granules of thrombin-activated platelets. These reactions generate AMP and ADP from Ap3A cleavage, and AMP and ATP from Ap4A cleavage. ENPP-4 is expressed on the surface of vascular endothelial cells where its activity prolongs platelet aggretation and contributes to thrombus formation.
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Additional ENPP-4 Products
Product Documents for ENPP-4 Antibody - BSA Free
Product Specific Notices for ENPP-4 Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.