Cytokeratin 7 Antibody (KRT7/1198) [DyLight 755]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47944IR
      Conjugate
              Catalog #
              
            Forumulation
              Catalog #
              
            Key Product Details
Species Reactivity
                  Human, Rat
                
                                                                                        Applications
                  CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot
                
                                                              Label
            DyLight 755 (Excitation = 754 nm, Emission = 776 nm)
          
        Antibody Source
            Monoclonal Mouse IgG1  kappa Clone # KRT7/1198
          
        Concentration
            Please see the vial label for concentration. If unlisted please contact technical services.
          
        Product Specifications
Immunogen
                          Recombinant full-length human Cytokeratin 7 protein (Uniprot: P08729)
                      
        Localization
                          Cytoplasmic
                      
        Specificity
                          It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This monoclonal antibody is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This monoclonal antibody is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
                      
        Marker
                          Glandular and Transitional Epithelial Marker
                      
        Clonality
                          Monoclonal
                      
        Host
                          Mouse
                      
        Isotype
                          IgG1  kappa
                      
        Applications for Cytokeratin 7 Antibody (KRT7/1198) [DyLight 755]
          Application
        
        
          Recommended Usage
        
      CyTOF-ready
                                                Optimal dilutions of this antibody should be experimentally determined.
                                                            
                  Flow Cytometry
                                                Optimal dilutions of this antibody should be experimentally determined.
                                                            
                  Immunocytochemistry/ Immunofluorescence
                                                Optimal dilutions of this antibody should be experimentally determined.
                                                            
                  Immunofluorescence
                                                Optimal dilutions of this antibody should be experimentally determined.
                                                            
                  Immunohistochemistry
                                                Optimal dilutions of this antibody should be experimentally determined.
                                                            
                  Immunohistochemistry-Paraffin
                                                Optimal dilutions of this antibody should be experimentally determined.
                                                            
                  Western Blot
                                                Optimal dilutions of this antibody should be experimentally determined.
                                                            
                  
        Application Notes
      
      
        Optimal dilution of this antibody should be experimentally determined.
      
    Formulation, Preparation, and Storage
Purification
                          Protein A or G purified 
                      
        Formulation
                          50mM Sodium Borate
                      
        Preservative
                          0.05% Sodium Azide
                      
        Concentration
                          Please see the vial label for concentration. If unlisted please contact technical services.
                      
        Shipping
                          The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
                      
        Stability & Storage
                          Store at 4C in the dark.
                      
        Background: Cytokeratin 7
Alternate Names
            CK-7, CK7, K2C7, K7
          
        Gene Symbol
            KRT7
          
        Additional Cytokeratin 7 Products
Product Documents for Cytokeratin 7 Antibody (KRT7/1198) [DyLight 755]
Product Specific Notices for Cytokeratin 7 Antibody (KRT7/1198) [DyLight 755]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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