Cyclin L2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Cyclin L2 Antibody [NBP2-47497]

Immunocytochemistry/Immunofluorescence: Cyclin L2 Antibody [NBP2-47497] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.

Immunohistochemistry-Paraffin: Cyclin L2 Antibody [NBP2-47497]

Immunohistochemistry-Paraffin: Cyclin L2 Antibody [NBP2-47497] - Staining of human colon tissue. Shows strong nuclear positivity in glandular cells.

Western Blot: Cyclin L2 Antibody - BSA Free [NBP2-47497] -

Phosphorylated SAMHD1 loses the ability to inhibit EV71 replicationAStable sh‐SAMHD1 HEK293T cells were transfected with VR1012, SAMHD1 WT, or the indicated mutant for 24 h and then infected with EV71 at a MOI of 0.05 for 72 h. Cells were harvested and subjected to IB analysis.BIB analysis of T592‐phosphorylated SAMHD1 and total SAMHD1 in RD and HEK293T cells.CThe effect of TRIM21 on endogenous phosphorylated SAMHD1 and total SAMHD1.DThe effect of TRIM21 on ectopic phosphorylated and unphosphorylated SAMHD1.E, FTRIM21 directly induced the degradation of SAMHD1 but not via changing cell cycle or upregulating cyclin L2 expression. (E) TRIM21 has no effect on the G0–G1 transition in MDM. (F) TRIM21 has no effect on the expression of cyclin L2 in MDM.Data information: (A–F) Tubulin served as a loading control.Source data are available online for this figure. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/31797533), licensed under a CC-BY license. Not internally tested by Novus Biologicals.