Key Product Details

Species Reactivity

Mouse

Applications

Blockade of Receptor-ligand Interaction, Flow Cytometry, Immunocytochemistry, CyTOF-ready

Label

mFluor Violet 500 SE (Excitation = 410 nm, Emission = 501 nm)

Antibody Source

Monoclonal Rat IgG2B Clone # 237603

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cripto Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Cripto
Arg26-Gln150
Accession # P51865

Specificity

Detects mouse Cripto in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ART, recombinant mouse (rm) ART, rmArtemin, recombinant drosophila DPP, rhGDNF, recombinant rat (rr) GDNF, rhLAP, rhLatent TGF-beta 1, rhTGF-beta 2, rhLefty-A, rmLefty-1, rrMIS, rhNeurturin, rmNodal, rhTGF-alpha, rhTGF-beta 1, rhTGF-beta 1.2, rhTGF-beta 3, or recombinant amphibian TGF-beta 5 is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Applications for CRIPTO Antibody (237603) [mFluor Violet 500 SE]

Application
Recommended Usage

Blockade of Receptor-ligand Interaction

Optimal dilutions of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Cripto

Teratocarcinoma-derived growth factor 1 (TDGF1), also known as CRIPTO, is expressed both in ES cells and during the early phases of embryo development. During development, CRIPTO is thought to play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. In adults, it is reactivated in a wide range of epithelial cancers.

CRIPTO-1 antibodies are useful tools for studying embryonic development and certian cancers.

Long Name

Teratocarcinoma-derived Growth Factor/Cripto Growth Factor

Alternate Names

CFC-2, TDGF-1, TDGF1

Gene Symbol

TDGF1

Additional Cripto Products

Product Documents for CRIPTO Antibody (237603) [mFluor Violet 500 SE]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CRIPTO Antibody (237603) [mFluor Violet 500 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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