Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 540802

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Collagen XXV alpha 1 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Collagen XXV alpha1
Gly189-Lys654
Accession # NP_942014

Specificity

Detects human Collagen XXV alpha1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) COL1A1, rhCOL3A1, rhCOL4A1, rhCOL13A1, rhCOL23A1 and recombinant mouse COL13A1 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Collagen XXV alpha 1 Antibody (540802) [DyLight 405]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Collagen XXV alpha 1

Antibodies against senile plaque (SP) amyloid obtained a clone which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer's disease (AD) brains. The antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD.

Alternate Names

COL25A1

Gene Symbol

COL25A1

Additional Collagen XXV alpha 1 Products

Product Documents for Collagen XXV alpha 1 Antibody (540802) [DyLight 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Collagen XXV alpha 1 Antibody (540802) [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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