CoCoA Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88215

Novus Biologicals, part of Bio-Techne
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NBP1-88215
NBP1-88215-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CoCoA Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EAEDEKSVLMAAVQSGGEEANLLLPELGSAFYDMASGFTVGTLSETSTGGPATPTWKECPICKERFPAESDKDALEDHMDGHFF

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (87%), Rat (89%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit CoCoA Antibody - BSA Free (NBP1-88215) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. Anti-CoCoA Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CoCoA Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: CoCoA Antibody [NBP1-88215]

Immunocytochemistry/ Immunofluorescence: CoCoA Antibody [NBP1-88215]

Immunocytochemistry/Immunofluorescence: CoCoA Antibody [NBP1-88215] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
Immunohistochemistry-Paraffin: CoCoA Antibody [NBP1-88215]

Immunohistochemistry-Paraffin: CoCoA Antibody [NBP1-88215]

Immunohistochemistry-Paraffin: CoCoA Antibody [NBP1-88215] - Staining of human breast shows strong cytoplasmic positivity in glandular cells.
CoCoA Antibody

Western Blot: Rabbit Polyclonal CoCoA Antibody [NBP1-88215]

Western Blot: Rabbit Polyclonal CoCoA Antibody [NBP1-88215] - Expression of CALCOCO1 in VA-13 cells (mouse ADH1-transfected HepG2 cells): control, alcohol-treated, treated with CALCOCO1 siRNAs, and CALCOCO1 siRNAs and alcohol. Beta-actin is a loading control. Image from a verified customer review.
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Applications for CoCoA Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Reviewed Applications

Read 1 review rated 5 using NBP1-88215 in the following applications:

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CoCoA

HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.

Alternate Names

calcium binding and coiled-coil domain 1, Calphoglin, Cocoa, Coiled-coil coactivator protein, coiled-coil leucine zipper coactivator 1, inorganic pyrophosphatase activator, KIAA1536calcium-binding and coiled-coil domain-containing protein 1, Sarcoma antigen NY-SAR-3

Gene Symbol

CALCOCO1

Additional CoCoA Products

Product Documents for CoCoA Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CoCoA Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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