CD45RC Antibody (C455.1F) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28135

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NBP1-28135
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Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, Immunoprecipitation

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # C455.1F

Concentration

0.1 mg/ml

View all CD45RC Antibodies »

Product Specifications

Immunogen

An exon C-dependent epitope of CD45 glycoprotein

Reactivity Notes

Mouse.

Specificity

An exon C-dependent epitope of CD45 glycoprotein

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for CD45RC Antibody (C455.1F) [PE]

Flow Cytometry: CD45RC Antibody (C455.1F) [PE] [NBP1-28135] - Cells from BALB/c spleen were double stained with rat anti-CD45RC-R-PE and rat anti-mouse CD8a-FITC (Clone 53-6.7), following which small lymphocytes were gated and analyzed on a Flow cytometer

Applications for CD45RC Antibody (C455.1F) [PE]

Application
Recommended Usage

Flow Cytometry

0.2 ug/10^6 cells

Immunoprecipitation

1:10-1:500

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS and a stabilizing agent

Preservative

Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD45RC

The CD45 family of cell-surface glycoprotein antigens exist as a set of isoforms. (1-4) The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T-200 species. (1-4) The 'restricted' subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. (1)

Alternate Names

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Gene Symbol

PTPRC

Additional CD45RC Products

Product Documents for CD45RC Antibody (C455.1F) [PE]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CD45RC Antibody (C455.1F) [PE]

Protect conjugated forms from light.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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