CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09052

Recombinant Monoclonal Antibody. Clone G28-1 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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NBP3-09052-0.025mg
NBP3-09052-0.2mg
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # G28-1

Format

Azide and BSA Free

Concentration

1 mg/ml

View all CD37 Antibodies »

Product Specifications

Immunogen

This antibody was raised by immunizing mice with CD37.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Description

Novus Biologicals Rabbit CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free (NBP3-09052) is a recombinant monoclonal antibody validated for use in Flow and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free

Immunocytochemistry/ Immunofluorescence: CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free [NBP3-09052]

Immunocytochemistry/ Immunofluorescence: CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free [NBP3-09052]

Immunocytochemistry/Immunofluorescence: CD37 Antibody (G28-1) - Chimeric [NBP3-09052] - Immunofluorescence analysis of paraformaldehyde fixed Daudi cells on Shi-fix(TM) coverslips stained with the chimeric rabbit IgG version of G28-1 (NBP3-09052) at 10 ug/ml for 1h followed by Alexa Fluor(R) 488 secondary antibody (2 ug/ml), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom NBP3-09052, DAPI, merged channels and an isotype control. The isotype control was an unknown specificity antibody followed by staining with Alexa Fluor(R) 488 secondary antibody.
Flow Cytometry: CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free [NBP3-09052]

Flow Cytometry: CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free [NBP3-09052]

Flow Cytometry: CD37 Antibody (G28-1) - Chimeric [NBP3-09052] - Analysis of Daudi cells

Applications for CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

G28-1 antibody was used to deplete normal and malignant B cells (Hayden-Ledbetter, unpublishesd). This antibody and antibody fragments derived therefrom have been used in the research and trials on the generation of novel immunotherapuetic agents, alternative to anti-CD20 therpaies (rituximab) (Robak and Robak, 2014).

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

0.02% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD37

CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

Alternate Names

CD37, TSPAN26

Gene Symbol

CD37

Additional CD37 Products

Product Documents for CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD37 Antibody (G28-1) - Chimeric - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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