beta-Defensin 3 Antibody - BSA Free

Immunohistochemistry-Paraffin: beta-Defensin 3 Antibody - BSA Free [NB200-117]

beta-Defensin-3-Antibody-Immunohistochemistry-Paraffin-NB200-117-img0002.jpg

Immunohistochemistry-Paraffin: beta-Defensin 3 Antibody - BSA Free [NB200-117]

Immunohistochemistry-Paraffin: beta-Defensin 3 Antibody [NB200-117] - Analysis of beta-Defensin 3 in human skin.

Immunohistochemistry: beta-Defensin 3 Antibody - BSA Free [NB200-117] -

Immunohistochemistry: beta-Defensin 3 Antibody - BSA Free [NB200-117] - Topical application of PALA enhances AMP production in human skin explants. (a) HBD2 protein levels are increased in tissue homogenates of infected human skin explants by PALA or Neosporin treatment. Human skin biopsies were infected with MRSA for 1 h & then treated with the indicated ointments for 24 hours in triplicate. HBD2 levels were measured in tissue homogenates by ELISA (n = 3–4 donors). Mean ± SD; significance determined by 1-way ANOVA & Bonferroni multiple comparison test; *p < 0.05. (b) Immunohistochemistry staining of HBD2 in MRSA infected human skin explants described in (a). Representative image of 3 donors. (c) HBD3 protein levels in tissue homogenates of infected human skin explants are unaffected by PALA or Neosporin treatment. HBD3 levels were measured in tissue homogenates described in (a) by ELISA (n = 4 donors). Mean ± SD; significance determined by 1-way ANOVA & Bonferroni multiple comparison test; p > 0.05. (d) Immunohistochemistry staining of HBD3 in MRSA infected human skin explants described in (a). Representative image of 4 donors. (e) LL-37 protein levels are increased in tissue homogenates of infected human skin explants by PALA treatment. LL-37 levels were measured in tissue homogenates described in (a) by ELISA (n = 4–5 donors). Mean ± SD; significance determined by 1-way ANOVA & Bonferroni multiple comparison test; *p < 0.05. (f) Immunohistochemistry staining of LL-37 in MRSA infected human skin explants described in (a). Representative image of 6 donors. Image collected & cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/29880914), licensed under a CC-BY license. Not internally tested by Novus Biologicals.