Skip to main content

BCR/ABL Antibody (4C12) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2665

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Radioimmunoassay

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 4C12

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

BCR/ABL peptide

Localization

Cytoplasmic

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse BCR/ABL Antibody (4C12) - BSA Free (NB100-2665) is a monoclonal antibody validated for use in IHC and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Applications for BCR/ABL Antibody (4C12) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:40 - 1:80

Immunohistochemistry

1:10 - 1:500

Radioimmunoassay

1:100 - 1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BCR/ABL

The BCR gene is involved in the 9:22 translocation that generates the Philadelphia chromosome both in chronic myeloid leukemia (CML) and in a proportion of cases of acute lymphocytic leukemia (ALL). A 5' bcr sequence becomes fused to an abl sequence (including tyrosine kinase domain sequences) from chromosome 9 and results in the production of a chimaeric BCR-ABL protein with enhanced kinase activity. These antibodies may be useful for studies of the oncogene and have potential diagnostic and prognostic applications.

Alternate Names

ABL, ALL, BCR ABL fusion protein, bcr/abl, BCR/ABL fusion protein, Bcr/c abl oncogene protein, BCR-ABL fusion protein, BCRe18/ABL1e3 fusion protein, breakpoint cluster region protein, c-ABL, CML, D22S662, JTK7, p150, PHL

Entrez Gene IDs

613 (Human)

Gene Symbol

BCR

UniProt

Additional BCR/ABL Products

Product Documents for BCR/ABL Antibody (4C12) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BCR/ABL Antibody (4C12) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Loading...
Loading...
Loading...
Loading...