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BAP1 Antibody (BAP1/9120R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-49011

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-49011-100ug
NBP3-49011-20ug

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # BAP1/9120R expressed in HEK293

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant fragment (around aa500-729) of human BAP1 protein (exact sequence is proprietary) (Uniprot: Q92560)

Localization

Nucleus, Cytoplasm

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Theoretical MW

91 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Scientific Data Images for BAP1 Antibody (BAP1/9120R)

BAP1 Antibody (BAP1/9120R)

Immunohistochemistry-Paraffin: BAP1 Antibody (BAP1/9120R) [NBP3-49011] -

Formalin-fixed, paraffin-embedded human breast carcinoma stained with BAP1 Antibody (BAP1/9120R). Inset: PBS instead of primary antibody; secondary only negative control.
BAP1 Antibody (BAP1/9120R)

Immunohistochemistry-Paraffin: BAP1 Antibody (BAP1/9120R) [NBP3-49011] -

Formalin-fixed, paraffin-embedded human breast carcinoma stained with BAP1 Antibody (BAP1/9120R). HIER: Tris/EDTA, pH9.0, 45min. 2�C: HRP-polymer, 30min. DAB, 5min.

Applications for BAP1 Antibody (BAP1/9120R)

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: BAP1

BRCA1-associated protein 1 (BAP1) is a ubiquitin hydrolase that acts as a BRCA1 growth control pathway tumor suppressor. Specifically, BAP-1 localizes to the nucleus where it interferes with the BRCA1/BARD1 heterodimer activity and mediates deubiquitination of histone H2A and HCFC1. BAP 1 is highly expressed in testis, placenta, breast and ovary.

Long Name

BRCA1-associated protein 1

Alternate Names

Cerebral Protein-6, UCHL2

Gene Symbol

BAP1

Additional BAP1 Products

Product Documents for BAP1 Antibody (BAP1/9120R)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BAP1 Antibody (BAP1/9120R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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