Skip to main content

ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44502

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
Loading...
NBP3-44502

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

ADC

Antibody Source

Monoclonal Human IgG1

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

ALCAM/CD166 (Uniprot: Q13740)

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Theoretical MW

145 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

This product is an Antibody-Drug Conjugate (ADC) for Research Use Only (RUO).

Praluzatamab Vedotin is an ADC consisting of an ALCAM-directed antibody and Monomethyl auristatin E (MMAE) used for the study of breast cancer.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

Hu ALCAM/CD166 mAb [ADC] - (Praluzatamab Vedotin)

Flow Cytometry: Hu ALCAM/CD166 mAb [ADC] - (Praluzatamab Vedotin) [NBP3-44502]

Human ALCAM/CD166 HEK293 Cell Line were stained with ALCAM/CD166 and negative control protein respectively, washed and then followed by PE and analyzed with FACS, The EC50 is 0.61 ug/mL.

Applications for ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

> 90% by SDS-PAGE and HPLC

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Background: ALCAM/CD166

Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic andhomophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as ininteractions between cells of the nervous system

Long Name

Activated Leukocyte Cell Adhesion Molecule

Alternate Names

CD166

Additional ALCAM/CD166 Products

Product Documents for ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ALCAM/CD166 Antibody [ADC] - (Praluzatamab Vedotin, Research Grade)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Loading...
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...