Caspase-6 Activity Assay Kit (Colorimetric)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-50232
Key Product Details
Sample Type & Volume Required Per Well
Cell and tissue samples
Product Specifications
Kit Type
Activity Assay Kit (Colorimetric)
Reactivity
Non-species specific
Description
Caspase 6, also known as Mch-2, was originally discovered in human Jurkat cells. The precursor of caspase 6 can be cleaved by granzyme B to form an activated caspase 6 dimer, which is found to induce apoptosis. Caspase 6 can cleave PARP and keratin-18, and also cleave Lamin A, a key component protein on the nuclear envelope. Only caspase 6 can cleave Lamin A in the caspase family. This caspase 6 activity assay kit is based on caspase 6 that can catalyze the substrate Ac-VEID-pNA to generate yellow pNA (p-Nitroaniline). The pNA has a strong absorption near 405 nm, The activity of caspase 6 can be calculated by determining the absorbance at 405 nm.
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C.
Background: Caspase-6
Alternate Names
CASP6, Caspase6, Mch2
Gene Symbol
CASP6
Additional Caspase-6 Products
Product Documents for Caspase-6 Activity Assay Kit (Colorimetric)
Product Specific Notices for Caspase-6 Activity Assay Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.
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