CCT 031374 hydrobromide

Name: CCT 031374 hydrobromide
Brand: Tocris Bioscience
SKU: 4675

Tocris Bioscience, part of Bio-Techne | Catalog # 4675

Citations (4)

COA / SDS

Inhibits TCF-dependent transcription; lowers β-catenin levels

Discontinued Product

4675 has been discontinued. View all beta-Catenin Inhibitors products.

Key Product Details

Description:	Inhibits TCF-dependent transcription; lowers β-catenin levels
Chemical Name:	1-[1,1'-Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanone hydrobromide
Purity:	≥98% (HPLC)
Molecular Weight:	434.33

View Full Technical Details for CCT 031374 hydrobromide

Technical Data
Citations

Biological Activity for CCT 031374 hydrobromide

CCT 031374 hydrobromide is an inhibitor of TCF-dependent transcription. Blocks BIO-induced β-catenin stabilization; reduces nuclear and cytosolic β-catenin levels in mouse L-cells. Inhibits growth and reduces TCF-dependent transcription in SW480 colon carcinoma cells.

Technical Data for CCT 031374 hydrobromide

M. Wt	434.33
Formula	C₂₃H₁₉N₃O.HBr
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	1219184-91-4
PubChem ID	18554738
InChi Key	MPILENOYNNNGKO-UHFFFAOYSA-N
Smiles	O=C(C4=CC=C(C5=CC=CC=C5)C=C4)CN1C3=C(C=CC=C3)N2C1=NCC2.Br

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for CCT 031374 hydrobromide

References are publications that support the biological activity of the product.

Ewan A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription. Cancer Res. 2010 PMID: 20610623

CCT 031374 hydrobromide

Tocris Bioscience, part of Bio-Techne | Catalog # 4675

Key Product Details

Biological Activity for CCT 031374 hydrobromide

Technical Data for CCT 031374 hydrobromide

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for CCT 031374 hydrobromide

Product Documents for CCT 031374 hydrobromide

COA

Certificate of Analysis

SDS

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