SMCy 5.5
Tocris Bioscience, part of Bio-Techne | Catalog # 7295
Key Product Details
| Description: | Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy |
| Chemical Name: | 6,8-Dicyclohexyl-4-((1E,3E,5E)-5-(1,1-dimethyl-3-(pent-4-yn-1-yl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-2,2-difluoro-2,8-dihydro-5H-1λ3,2λ4-[1,3,2]dioxaborinino[6,5-d]pyrimidine-5,7(6H)-dione |
| Purity: | ≥95% (HPLC) |
| Molecular Weight: | 693.64 |
Biological Activity for SMCy 5.5
Key information: SMCy 5.5 is a fluorogenic fluorescent probe for imaging lipid droplets. Supplied with an alkyne reactive handle for click chemistry. Suitable for deep tissue imaging and 3D imaging.
Application: Suitable for 2-photon excitation (2-PE) microscopy. Alkyne handle allows optional functionalization.
Properties and Photophysical Data: SMCy 5.5 exhibits sharp excitation and emission bands and high brightness. It displays high two-photon absorption (TPA) cross-section values (13330 GM and 10400 GM at 770 and 820 nm, respectively). Excitation and emission maxima (λ) for SMCy 5.5 in Tetrahydrofuran are 643nm and 672 nm, respectively; quantum yield = 0.75; extinction coefficient = 209,000 M-1 cm-1.
Optical Data for SMCy 5.5
| Emission Color | Far Red |
|---|---|
| Brightness | |
| λabs | 636 nm |
| λem | 660 nm |
| Extinction Coefficient (ε) | 194,000 M-1cm-1 |
| Quantum Yield (φ) | 1 |
| Closest Laser line | 640 nm |
| Reactive Group | Alkyne |
| Reactivity | Click |
| Cell Permeable | Yes |
| Application | 2PE Fluorescence Imaging, Deep Tissue Imaging, 3D Imaging |
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