Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated
R&D Systems, part of Bio-Techne | Catalog # S12550H
Key Product Details
Features
Key Benefits
- Manufactured from EU-approved origin material
- Heat-inactivated under a quality-controlled setting
- Excellent cell growth characteristics, low endotoxin, and low hemoglobin values
- Superior performance with a broad spectrum of cell types
- More affordable alternative to other commercially available FBS
- Available as 500 mL and 50 mL sizes
Applications
Product Summary for Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated
The objective of heat inactivation is to destroy complement activity in the serum without affecting the growth-promoting characteristics of the product. Removal of complement activity from the serum is not required for most cell cultures, but may be necessary for cultures that are sensitive to the complement activity. Researchers should evaluate the applicability of heat inactivation in regards to their own application.
Formulation, Preparation, and Storage
Shipping
Storage
Background: Fetal Bovine Serum (FBS)
Fetal bovine serum (FBS), also known as fetal calf serum (FCS), is a commonly used cell culture media supplement. It supplies growth factors, hormones, vitamins, and other nutrients that can support the proliferation and viability of cells in culture. The range of these factors provided by FBS enables the culture of a wide variety of cell types that may have uncharacterized culture requirements. Heat inactivation of FBS destroys potentially detrimental complement proteins while retaining the growth-promoting properties of the serum. Specialty grades of FBS are optimized for the culture of particular cell types such as hybridomas, embryonic stem cells, tetracycline-controlled expression systems, and hormone dependent cells for insulin- and estrogen-related research. Manufacturers of FBS control product variability by managing the raw material supply chain, adhering to consistent processing protocols, and rigorous testing to ensure low endotoxin, hemoglobin, and virus load. USDA-approved testing of FBS is important to certify the virus and disease safety of the source before importing animal material into the United States. USDA APHIS certification enables the use of our US origin serum for the manufacture and export of products outside of the USA.
Product Documents for Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated
Product Specific Notices for Fetal Bovine Serum (FBS) – EU-approved, Heat-Inactivated
FOR LABORATORY RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
- The safety and efficacy of this product in diagnostic or other clinical uses has not been established.
- This reagent should not be used beyond the expiration date indicated on the label.
- Results may vary due to variations among cells or cell lines used.